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From126US$ /night
Check-in
27Nov2025Select date
Check-out
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Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

421 West B Street, San Diego, California, United States, 92101
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Positioned nearly 15 minutes' walk from the historical naval aircraft carrier USS Midway Museum and merely 1.6 km from the primary San Diego Convention Center, the 4-star modern Hotel Republic San Diego, Autograph Collection provides a ballroom for a variety of uses. Nestled in the vicinity of Little Italy, this smoke-free hotel features 2 restaurants serving American and local cuisine.

Location

The hotel is located in old part of San Diego, 250 m from American Plaza. The luxury Republic gives access to the lush park "Botanical Building", which is approximately 25 minutes' walk away.

The property is about 400 metres from India St & C St bus stop and right around the corner from Santa Fe Depot train station in San Diego. This hotel is notable for the convenient location 5 km from San Diego International airport.

Rooms

There are 284 rooms at Hotel Republic San Diego, Autograph Collection, each of them has an ironing set and climate control, as well as entertainment amenities such as a flat-screen TV with satellite channels. Bathrooms include a separate toilet and a shower, along with hair dryers and bath sheets. They offer views of the city.

Eat & Drink

The American-style restaurant in the Republic San Diego serves dinner, while in the à la carte restaurant guests can enjoy their breakfast. The restaurant at the accommodation has American menu. Also, this San Diego hotel features a lounge bar. The restaurant Animae is located around 5 minutes on foot from the Republic San Diego.

Leisure & Business

In order to stay active, guests can use yoga instruction, elliptical machines, and treadmills at this San Diego hotel. As part of its commitment to guest wellness, the accommodation includes a fitness studio featuring fitness classes.

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Select your room type

The hotel provides many room choices—family rooms, doubles, and pet-friendly suites—with breakfast, free cancellation, and special offers
Standard King Room
2 persons
34 m² 
1 King-size bed
Shower
Heating
Standard King Room City View
2 persons
34 m² 
1 King-size bed
Shower
Heating
Standard King Room High Floor
2 persons
34 m² 
1 King-size bed
Shower
Heating
Executive Corner King Room
2 persons
54 m² 
1 King-size bed
Shower
Heating
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Rates & availability calendar

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Local transport and travel tips

Overview of transport options available

City Centre
San Diego 1.4 km
Airports
San Diego International (SAN) 4.0 km
El Cajon (CJN) 25.3 km
Train
Santa Fe Depot300 m
Coaster Santa Fe Station300 m
Bus
Bus stop200 m

Facilities

Hotels feature amenities designed to keep both you and your pet comfortable

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Luggage storage
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Smoke detectors
  • Electric vehicle charging station
  • Fire extinguishers
  • Key card access

Sports & Fitness

  • Fitness centre
  • Yoga class

Services

  • Valet parking
  • Pet amenities available
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Welcome drink
  • Happy hour

Dining

  • Restaurant
  • Bar/ Lounge area

Business

  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Cots
  • Children's menu

Facilities for people with disabilities

  • Toilet for disabled
  • Bathroom for disabled

Spa & Leisure

  • Live entertainment
  • Leisure/ TV room

Room features

  • Air conditioning
  • Heating
  • Sitting area
  • Terrace
  • Garden furniture
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Carpeted floor
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Hotel location

421 West B Street, San Diego, California, United States, 92101
Map view
421 West B Street, San Diego, California, United States, 92101
Nearby
Train Station
Santa Fe Depot
380 m
Museum
San Diego Firehouse Museum
520 m
Museum
Museum of Contemporary Art
370 m
Church
Our Lady of the Rosary Catholic Church
520 m
Restaurants
Kelvin
0 m
421 W B St
Carnivore Sandwhich
180 m
670 W B St
Luca
310 m
500 West Broadway
Extraordinary Desserts
400 m
1430 Union Street
Aaharn by Koon Thai
260 m
1202 Kettner Blvd Suite 104
Petrini's Italian Restaurant
390 m
610 W Ash St
Tender Greens
470 m
110 W Broadway
Fabrison's
410 m
1425 India Street
King and Queen Cantina
440 m
1490 Kettner Blvd
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Check-in
27Nov2025Select date
Check-out
28Nov2025Select date
Rooms and Guests2 Guests, 1 Room